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Fifty years ago today, thousands of parents drove their school-age children to designated sites across the country for immunizations of an experimental vaccine that they hoped would stop, once and for all, the raging polio epidemic that was leaving young Americans paralyzed and sometimes dead. Organized and funded by the March of Dimes, this was the largest voluntary clinical trial ever undertaken.
"For mothers around the world, preparing the family meal is a daily ritual and an act of love. But it's also a grave risk for approximately three billion people who cook with open fires and inefficient stoves that burn solid fuels such as wood, animal and agricultural waste, and coal," Kathy Calvin, CEO of the United Nations Foundation, writes in the Huffington Post's "Global Motherhood" blog.
Autism Speaks is encouraged by yesterday's decision of the Interagency Autism Coordinating Committee (IACC) to include vaccine research studies in the objectives of the updated Strategic Plan for Autism Research. The new language, approved unanimously, calls for studies to determine if there are sub-populations that are more susceptible to environmental exposures such as immune challenges related to naturally occurring infections, vaccines or underlying immune problems.
A study conducted by researchers in the US has revealed that optimization of codon for bacterial expression causes the production of an inactive enzyme non-structural protein 12 (Nsp12), a catalytic subunit of RNA-dependent RNA polymerase of SARS-CoV-2.
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