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A new study led by researchers at The Saban Research Institute of Children's Hospital Los Angeles reports that the presence of leptin - a hormone secreted by fat cells that is critical to maintaining energy balance in the body - inhibits the prenatal development of neuronal connections between the brain and pancreas. The findings could help explain the origin of type 2 diabetes, particularly in children of obese mothers.
The science of measuring drug levels in the blood after death is far from robust and based on flawed evidence - leading to likely miscarraiges of justice and conspiracy theories, say forensic scientists in this week's BMJ.
Treatment with the diabetes drug liraglutide, in combination with diet and exercise, led to a significant reduction in weight and improved a number of cardiovascular risk factors, including high blood pressure and high cholesterol, according to a multicenter study.
Physiotherapy can improve the daily lives of patients who have had knee replacement surgery due to osteoarthritis in the short term, according to a study published on bmj.com.
Addressing the question of whether the international community can eliminate tuberculosis, Arundhati Maitra and Sanjib Bhakta of the Department of Biological Sciences at the University of London write in an opinion piece in the AlertNet News Blog, "With an estimated 8.7 million reported cases and 1.4 million deaths due to TB in 2011, the question above poses one of the most serious challenges faced by the scientific community, health care industry, government and public organizations worldwide."
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