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Scientists have traced the first steps in the way some new diseases emerge, and how harmless bacteria living in insects become dangerous disease-causing bugs which can affect humans, like the plague or anthrax.
Regulus Therapeutics Inc. today announced the establishment of a new collaboration with GlaxoSmithKline (GSK) to develop and commercialize microRNA therapeutics targeting microRNA-122 in all fields with Hepatitis C Viral infection (HCV) as the lead indication. Under the terms of the new collaboration, Regulus will receive additional upfront and early-stage milestone payments with the potential to earn more than $150 million in miR-122-related combined payments, and tiered royalties up to double digits on worldwide sales of products.
Runners who consistently log high mileage show more neuromuscular changes that improve running efficiency than their low-mileage counterparts, according to researchers from Liverpool John Moores University in the United Kingdom.
While it is established that nicotine by itself is not carcinogenic, researchers have now shown that nicotine promotes cell proliferation and the progression of tumors already initiated by tobacco carcinogens.
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