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Using dynamic contact maps and energy differences between different conformations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (or S-protein), an international team of researchers have recently published an article on the bioRxiv preprint server showing the different stable conformations of the spike protein.
A potentially explosive new study published on the preprint server medRxiv in June 2020 suggests that the official Chinese statistics on COVID-19 cases or mortality are neither reliable nor credible. If true, such unreliable data during a crucial period of the pandemic in February and March 2020 could have seriously skewed the response and preparation of the rest of the world and altered the future course of the viral pneumonic illness.
Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons - both significant contributors to this type of dementia.
The smoking cessation medications bupropion and varenicline may both be associated with changes in the way the brain reacts to smoking cues, making it easier for patients to resist cravings, according to two reports posted online today that will appear in the May print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
The human brain is a complex system comprising 1010 non-linear units (neurons) that interact in 1015 sites (synapses).
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