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Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, particularly in China. However, HCC remains one of the more difficult cancers to treat. It is important to screen for new anti-cancer drugs. A number of dietary compounds possess anti-cancer properties. These dietary compounds may modify the activity of specific targets that control cell proliferation and apoptosis. Galangin could inhibit the methoxyresorufin O-demethylase activity of CYP1A2, CYP1A1 and P-form phenolsulfotransferase.
Selcia has successfully completed 14C radiolabelled API projects on behalf of a diverse range of clients for phase 1 human trials, following MHRA GMP Certification in September 2010. In response to a sharp increase in demand for this specialist service, Selcia has invested to double its capacity for handling GMP radiolabelling projects.
Current public health guidelines recommend that only gay men and people with HIV should be routinely screened for extragenital gonorrhea and chlamydia, given the high burden of these sexually transmitted infections (STIs) in this at-risk population.
Over 90 percent of those operated on for congenital heart defects as children, for example, due to blue baby syndrome, are alive 20 years post-surgery. A new doctoral thesis at Sahlgrenska Academy has explored this issue.
In the culmination of decades of research at the University of Virginia Health System, doctors have begun human testing of a drug they hope will one day save many lives among lung transplant recipients.
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