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Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University of Illinois at Chicago College of Medicine.
A new study reports the use of a modified deoxyribonucleic acid (DNA) oligonucleotide that has a 3' polyadenine (polyA) tail to bind to the 5'-polyU tract in the mouse coronavirus (MHV-A59). Treatment of mouse cells infected with MHV-A59 with this molecule led to a marked reduction in cell deaths.
Fallout from recent mass killings involving the mentally ill have states scrambling to figure out how to best treat these patients as well as considering stricter gun controls - which, in turn, is drawing the ire of the National Rifle Association.
Overly strict interpretation of the data protection law is hampering epidemiological research (the study of the causes, distribution, and control of disease in populations), argue researchers in this week's British Medical Journal.
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