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Ember Therapeutics, Inc., a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key preclinical data demonstrating that inhibition of the Transient Receptor Potential Vanilloid (TRPV) family of ion channels - specifically TRPV4 - resulted in activation of brown/beige fat and protection from diet-induced obesity, inflammation and insulin resistance. Ember holds an exclusive option to license these TRPV4 findings and technology.
PRA International, a leading Clinical Research Organization, announces the opening of a new Phase I facility in Prague, Czech Republic that will provide innovative "unit-on-demand" services and further enhance our capabilities for conducting early development trials.
The National Institute of Allergy and Infectious Diseases has awarded the Perelman School of Medicine at the University of Pennsylvania a five-year, $10 million renewal of a program project to study the oldest part of the human immune system called the complement system, or simply "complement."
Researchers at the Translational Genomics Research Institute have identified a genomic mutation that causes physical abnormalities and developmental delays in children.
"Former U.S. president Bill Clinton, who is now the U.N. special envoy to Haiti, announced the appointment Tuesday of Harvard professor Paul Farmer, a pioneer in community health treatment for the world's poor, as his deputy," the Associated Press/mlive.com reports (8/11).
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