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A new mathematical model of the structure of networks could help find new cancer drugs, speed up traffic flow and combat sexually transmitted disease.
Understanding the cellular response to DNA strand breaks is crucial to decipher the mechanisms maintaining the integrity of our genome. In eukaryotic cells, the molecular events triggered by DNA damage are strongly influenced by the local chromatin environment surrounding the lesion. The ensuing DNA repair process, in turn, impacts on chromatin structure. In order to understand how these two fundamental processes are mutually connected, both chromatin rearrangements induced by DNA damage as well as DNA repair activity have to be visualized in living cells.
"Since 1970, campaigns against smoking seem to have been largely successful, but the message has not been able to reach the youngest ages," says professor Cecilie Svanes at Centre for International Health at The University of Bergen.
A highly underutilized anesthesia technique called neuraxial anesthesia, also known as spinal or epidural anesthesia, improves outcomes in patients undergoing hip or knee replacement, according to a new study by researchers at Hospital for Special Surgery.
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