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Vertex Pharmaceuticals Incorporated today announced the final results from its pivotal Phase 3 STRIVE study that evaluated VX-770, a medicine in development that targets the defective protein that causes cystic fibrosis (CF).
The authors note that hospitals need detailed data about postdischarge (PD) complications among surgical patients in order to develop "appropriate quality improvement interventions and potentially avoid reimbursement penalties." In attempt to bridge this knowledge gap, researchers from Yale and Stanford Universities evaluated procedure types, rates and risk factors for PD complications occurring within 30 days after 21 groups of inpatient general surgery procedures for more than 500,000 patients.
The U.S. Food and Drug Administration today approved Promacta (eltrombopag) to treat low blood platelet count in pediatric patients – ages one year and older – with a rare blood disorder called chronic immune thrombocytopenic purpura (ITP). Promacta can be used in these children when they have not achieved an appropriate response using other ITP medicines or surgery to remove the spleen.
When the targeted drug bortezomib stops working in patients with advanced multiple myeloma, the patients survive only an average of five months longer. But a phase 2 clinical trial has shown that pairing bortezomib with an experimental drug, panobinostat, may be a promising new treatment for such patients, Dana-Farber Cancer Institute researchers say.
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