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A new test that combines the effects of more than two dozen genetic variants, most associated by themselves with only a small risk of Alzheimer's disease, does a better job of predicting which cognitively normal older adults will go on to develop Alzheimer's dementia than testing only for the well-known genetic variant APOE E4, a scientific team led by researchers at UC San Francisco and UC San Diego has found.
The Indiana University School of Medicine Department of Psychiatry seeks participants for a study on the effectiveness of an investigational medication for adults with Attention Deficit-Hyperactivity Disorder. The research study also will examine the impact of adult ADHD on families.
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro- and anti-fibrotic response.
David Martin, who helped write Governor Deval Patrick's health care payment reform bill, is leaving. Martin, the Director of Health Care Policy and Strategy in the office of Health and Human Services, is taking a job at Covidien as Senior Director of Health Care Economics and Policy.
Drug molecules seldom act simply on one protein but on protein complexes and networks. A deeper understanding of these 'cooperative assemblies' should lead to better targeting of drugs.
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