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After the left ventricle of the heart contracts, it must relax efficiently to prepare to refill and supply the body with blood on the next beat. An increasing number of patients - including nearly all patients with heart failure - suffer from impaired relaxation, which is part of a clinical syndrome known as diastolic dysfunction. Currently, treatments for impaired relaxation do not exist.
Eikonoklastes Therapeutics, a preclinical stage biopharmaceutical company developing next-generation tissue factor (TF) immunotherapies for triple-negative breast cancer (TNBC) and several other diseases with unmet clinical need, today announced closing of an oversubscribed seed financing.
Being at the top has its perks, but new UofT research shows people in positions of authority at work are more likely to experience certain psychological and physical problems that can undermine the health benefits associated with job authority.
Almost 60 per cent of truck drivers in a recent Canadian study reported experiencing musculoskeletal pain and discomfort on the job, even though it may be preventable.
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