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AVEO Oncology (NASDAQ: AVEO) and Astellas Pharma Inc. (TSE: 4503) announced overall survival (OS) for tivozanib, an investigational agent, from the Phase 3 TIVO-1 (TIvozanib Versus sOrafenib in 1st line advanced RCC) study in patients with advanced renal cell carcinoma (RCC). The final OS analysis, as specified by the protocol, shows a median OS of 28.8 months (95% confidence interval [CI]: 22.5–NA) for tivozanib versus a median OS of 29.3 months (95% CI: 29.3–NA) for the comparator arm, sorafenib.
If you want to learn to walk a tightrope, it's a good idea to go for a short run after each practice session. That's because a recent study in NeuroImage demonstrates that exercise performed immediately after practicing a new motor skill improves its long-term retention.
Previous studies have demonstrated that fetal malnutrition can lead to adult chronic disorders such as type 2 diabetes and coronary artery disease. A new study out of China now suggests that it also can lead to early menopause and premature ovarian failure.
Biological siblings of people with gambling disorder also display markers of increased impulsivity and risk-taking, according to a new UBC psychology study. The findings, published today in Neuropsychopharmacology, suggest people with gambling disorder - a psychiatric term for serious gambling problems - may have pre-existing genetic vulnerabilities to the illness.
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