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A two-year trial of entecavir followed by lamivudine (LAM) in patients with chronic hepatitis B virus (HBV) infection resulted in a virologic rebound rate of 24% and 12% drug-resistance rate. Patients who continued on entecavir therapy throughout the study period had undetectable HBV DNA at the two-year endpoint. Details of this trial are published in the April issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.
Stroke survivors have about twice the risk of breaking a hip or femur compared to those without stroke - and the risk is even greater for younger patients, women and those with recent strokes, Dutch researchers report in Stroke: Journal of the American Heart Association.
The National Heart, Lung and Blood Institute of the National Institutes of Health has awarded a five-year grant of $15.6 million to Karina Yazdanbakhsh, PhD, of New York Blood Center's Lindsley F. Kimball Research Institute, to lead a collaborative research program studying the consequences of transfusions in patients with sickle cell disease and developing strategies to optimize transfusion management for this patient group.
The Canadian Nurses Association (CNA) welcomes the appointment of Anne Doig as president of the Canadian Medical Association and applauds her call for action on introducing change to Canada's health-care system.
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