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News Archive
Fear and fear extinction learning are adaptive processes caused by molecular changes in specific brain circuits, and they're perturbed in conditions such as anxiety and post-traumatic stress disorder.
An analysis of 48,785 HIV-positive patients enrolled in China's National Free Antiretroviral Treatment Program over a five-year period revealed that "[h]alf of China's AIDS patients stopped responding to treatment over five years and didn't have access to the back-up drugs available in developed nations," according to an Annals of Internal Medicine study, Bloomberg reports.
Scientists have identified a key enzyme responsible for destroying lung tissue in tuberculosis, they report today in the Journal of Clinical Investigation. Drugs that inhibit this enzyme are already available, meaning that the finding could lead quickly to new treatments.
According to a report drafted by the U.N. Economic Commission for Africa (UNECA) and the African Union (A.U.) Commission that reviews the Millennium Development Goals (MDGs) for Africa, the continent recorded a slight drop in infant, child, and maternal mortality in 2011, PANA/Afrique en ligne reports.
Santaris Pharma A/S, a clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, today announced that it has advanced into drug development a discovery research candidate directed against PCSK9 (proprotein convertase subtilisin/kexin type 9), an important new target for the treatment of high cholesterol. Using its proprietary Locked Nucleic Acid (LNA) Drug Platform and Drug Discovery Engine, Santaris Pharma A/S identified and advanced the new drug, SPC5001, in just 18 months.
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