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The Food and Drug Administration (FDA) ensures that high-risk medical devices, such as implantable cardioverter-defibrillators and pacemakers, are safe and effective through its premarket approval (PMA) pathway, during which manufacturers must collect preclinical and clinical data before the device is approved.
Last month more than 250,000 personalized leaflets were sent out to women with a warning that a Conservative government would scrap a Labour guarantee that all suspected breast cancer patients would be seen by a specialist within two weeks of GP referral. They also claimed that the Conservative party will take away the right to be treated for cancer within 18 weeks. According to a Sunday Times report some of the recipients of this leaflet were cancer patients or cancer survivors.
Daily sleeping and eating patterns are critical to human well-being and health. Now, a new study from Concordia University has demonstrated how the brain chemical dopamine regulates these cycles by altering the activity of the "clock-protein" PER2. Published in the Journal of Neuroscience, these findings may have implications for individuals with Parkinson's Disease with disrupted 24-hour rhythms of activity and sleep.
GlycoMimetics, Inc., a clinical stage biotechnology company developing a new class of glycobiology based therapies for a broad range of indications, today announced that the journal Blood has published pre-clinical data on the company's lead compound GMI-1070 in a model of sickle cell disease.
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