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A statistical model accounting for dozens of different genes in combination—and the interactions between them—is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America.
Johns Hopkins University researchers have received an estimated $7.5 million National Institutes of Health grant to clinically test what would be the first treatment to prevent or delay the onset of Alzheimer's dementia.
A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients' TB bacteria within two weeks and could be more effective than existing treatments, according to a study published today in the Lancet. These results add to a growing body of evidence that the new regimen could reduce treatment by more than a year for some patients.
A $250,000 grant from the Centers for Disease Control and Prevention (CDC) will support a Rhode Island Hospital research study aimed at reducing the state's leading cause of accidental death among adults. Researchers will explore the use and effectiveness of statewide prescription monitoring programs (PMP) in reducing the number of accidental overdose deaths involving prescription opioids like OxyContin and Vicodin in both Rhode Island and Connecticut.
Male fruit flies whose sexual advances are rejected by females, turn to alcohol finds a new study. Scientists at the University of California, San Francisco discovered that rejected male flies have a tiny molecule in their brain that pushes them to drink far more than their sexually satisfied counterparts. The levels of the molecule, neuropeptide F, were higher in sexually satisfied males than in those who got no sex, leading scientists to speculate that their work could shed light on brain mechanisms behind human addiction. A similar human molecule - neuropeptide Y - may also link social triggers to behaviors such as heavy drinking and drug abuse, according to the study published in Science journal.
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