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An international group of medical experts has crafted a much-needed classification system for diabetic nephropathy, the leading cause of total kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The effort should improve communication among health professionals, help researchers design better clinical studies, and guide patient care.
A California Institute of Technology -led team of researchers and clinicians has published the first proof that a targeted nanoparticle-used as an experimental therapeutic and injected directly into a patient's bloodstream-can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off an important cancer gene using a mechanism known as RNA interference (RNAi).
Cells in the nervous system can "put the brakes" on the immune response to infections in the gut and lungs to prevent excessive inflammation, according to research by Weill Cornell Medicine scientists. This insight may one day lead to new ways to treat diseases caused by unchecked inflammation, such as asthma and inflammatory bowel disease.
Novavax, Inc. today reported favorable initial results from the first stage of a two-stage pivotal Phase II study evaluating the safety and immunogenicity of the company's 2009 H1N1 virus-like particle (VLP) pandemic influenza vaccine. Novavax is conducting this study in collaboration with Avimex Laboratories of Mexico to support registration of the vaccine in Mexico and potentially other countries.
IBM scientists have been able to image the "anatomy" - or chemical structure - inside a molecule with unprecedented resolution, using a complex technique known as noncontact atomic force microscopy.
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