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Exelixis, Inc. announced today that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration for XL888, a novel anticancer compound. XL888 is an orally available small molecule inhibitor of HSP90, which is a chaperone protein that promotes the activity and stability of a range of key regulatory proteins, including kinases.
An optical fiber probe can distinguish cancer tissue and normal tissue at the margins of a tumor being excised, in real time, by detecting the difference in pH between the two types of tissue.
More people who have known coronary heart disease die from other causes — such as cancer, and lung and neurological diseases — than heart disease, compared with 20 years ago, according to a Mayo Clinic study published online today in Circulation, an American Heart Association journal.
In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.
Officials at the new Muhammad Ali Parkinson Center at Barrow Neurological Institute announced today the center's participation in a novel Parkinson's study aimed at determining the physical and neurological impact of simple exercise on Parkinson's patients.
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