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OPKO Health, Inc. today announced that it has entered into a definitive agreement with Schering-Plough Corporation to acquire assets relating to Schering's neurokinin-1 (NK-1) receptor antagonist program. Rolapitant, the lead product, recently completed Phase II clinical testing for prevention of nausea and vomiting related to cancer chemotherapy and surgery, and other indications.
The Critical Path Institute and Provention Bio, Inc. are proud to announce their collaboration to significantly improve the scientific community's insight into type 1 diabetes through Provention's contribution of data from the Phase III Protégé study of teplizumab to the T1D Trial Outcome Measures Initiative integrated database.
As scientists continue to search for effective antidotes to direct and indirect damage caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new preprint research paper posted to the bioRxiv* server demonstrates the potential of cannabinoid receptor agonists to alleviate myocardial damage in this condition even in the absence of any inhibitory effect on viral infection as such.
Researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, have found that an arsenic-based agent already FDA-approved for a type of leukemia may be helpful in another hard-to-treat cancer, Ewing's Sarcoma (ES). The research, based on animal studies, also suggests the drug might be beneficial in treating medulloblastoma, a highly malignant pediatric brain cancer.
In an international collaboration between MedUni Vienna, Semmelweis University in Budapest, the Karolinska Institute in Stockholm and Yale University in the USA, researchers have identified a new process in the brain that is responsible for the delayed stress response and the long-term effects of stress: with a delay of 10 minutes after the "danger", the area of the brain that reacts to stress and responsible for further action is activated via the cerebral fluid.
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