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Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, an international team of Ludwig researchers and their colleagues has established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues.
Researchers at the University of Colorado Anschutz Medical Campus have developed a unique model allowing them to predict which children arriving in emergency departments are most likely to go into septic shock, a life-threatening condition.
A new preprint deals with the analysis of the monoclonal antibody J08, which was capable of powerful neutralization of the wildtype SARS-CoV-2, and its VOCs.
The psychological and social risks that adolescents experience can have a lasting impact on adulthood.
Enthusiasm for an emerging digital health tool, the smart pill, is on the rise but researchers at the University of Illinois at Chicago have published a paper in the American Journal of Bioethics that cautions health care providers and policymakers to slow down when it comes to allowing this technology in patient care settings.
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