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One-year data from the PARTNER clinical trial, published today in the New England Journal of Medicine, demonstrate that transcatheter aortic-valve implantation, compared with standard therapy, resulted in significantly lower rates of death among patients who cannot undergo surgery for aortic stenosis. The results will be presented tomorrow as a Late Breaking Trial at the 22nd annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.
The first ever patient to have undergone gene therapy for Parkinson's appears to have come through phase I without a hitch, suggesting that the therapy is safe and effective, reports Marina Murphy in Chemistry & Industry.
Could drug addiction treatment of the future be as simple as an on/off switch in the brain? A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally.
"In October 1987, Roy Vagelos, then the chief executive of pharmaceutical company Merck, launched the largest pharmaco-philanthropic venture ever," William Foege, an epidemiologist and former director of the CDC, writes in a Washington Post opinion piece highlighting the company's efforts to combat onchocerciasis in the developing world through the free distribution of its drug Mectizan.
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