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New research by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington shows that innovative and improved methods for analyzing verbal autopsies - a method of determining individuals' causes of death in countries without a complete vital registration system - are fast, effective, and inexpensive, and could be invaluable for countries struggling to understand disease trends.
Just like teenagers at a prom, proteins are tended by chaperones whose job it is to prevent unwanted interactions among immature clients. And at the molecular level, just as at the high school gym level, it's a job that usually requires a lot of energy.
Ever since COVID-19 first emerged with devastating ferocity, the emphasis has been on interrupting its spread until effective, safe and targeted antivirals and vaccines become available. The chief focus has been on non-pharmaceutical interventions (NPIs), including school closures, social distancing and shelter in place orders.
Results from a Phase III program evaluating imiquimod 3.75% and 2.5% creams for the treatment of EGW, applied once daily for up to 8 weeks, demonstrated that both were well-tolerated and more efficacious than placebo, according to data presented at the annual Human Papillomavirus Conference in Montreal, July 3 - 8. Investigators found that efficacy was greatest for imiquimod 3.75% with an enhanced safety profile.
A mathematical model that can help project the contagiousness and spread of infectious diseases like the seasonal flu may not be the best way to predict the continuing spread of the novel coronavirus, especially during lockdowns that alter the normal mix of the population, researchers report.
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