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The Associated Press reports that Senate Finance Committee Chairman Max Baucus, D-Mont., said today as he began the panel's seventh day of mark-up that he "wanted to complete work on a sweeping health care bill by nightfall, opening the way for Democratic leaders to bring the historic legislation to the floors of both the House and Senate as early as mid-October." Once the Finance Committee finishes its deliberations on the measure, "Senate leaders can work to finalize a package to bring to the Senate floor."
Cytochroma today announced positive Phase I results for CTAP201 Injection, a product being developed to treat secondary hyperparathyroidism in hemodialysis patients. The study demonstrated that single intravenous doses of 1 and 3 mcg of CTAP201 were safe and well tolerated. It also identified a starting dose of 2 mcg for subsequent pivotal trials intended to establish the product's safety and efficacy in the targeted population.
In patients with rapid-cycling bipolar disorder, antidepressants can increase incidents of depression and mood cycling. Rif S. El-Mallakh, M.D., director of the Mood Disorders Clinical and Research Program at the University of Louisville, along with Nassir Ghaemi, M.D., of Tufts University and other researchers, conducted the first randomized clinical trial that analyzes how modern antidepressants affect patients with rapid-cycling (RC) bipolar disorder (BD).
Bioengineers from the University of California, San Diego developed an explanation for why some types of neurons die sooner than others in the brains of people with Alzheimer's disease. These insights, published in the journal Nature Biotechnology on November 21, come from detailed models of brain energy metabolism developed in the Department of Bioengineering at the UC San Diego Jacobs School of Engineering.
Researchers say that the Quality and Outcomes Framework that was introduced to UK general practice in 2004 may not be worth the expense of implementing it in terms of benefiting patients.
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