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With the estimated 1.2 million people with HIV/AIDS in the United States expected to live close to a normal life span, the majority of pharmaceutical companies are not developing innovative, new long-term treatment options that offer improved efficacy, safety and tolerability when taken for decades, according to a report card on the pharmaceutical industry released today by the AIDS Treatment Activists Coalition's (ATAC) Drug Development Committee.
Scientists and health officials are marshalling forces to fight Zika, the latest in a string of recent outbreaks. Many of these efforts target that virus specifically, but some researchers are looking for a broader approach. Now one team reports in ACS' journal Macromolecules a new strategy to fight a wide range of viruses that appears to be safe in vivo and could evade a virus's ability to develop resistance.
When health ministers gather for the World Health Assembly in May they will try to come up with a solution to "a dilemma that has dogged decision-makers for decades - whether and when to destroy the last remaining stocks of the smallpox virus," David Heymann and Emma Ross, both of the Global Health Security Centre at Chatham House, write in an article in The World Today.
The circadian clock system (from Latin "circa diem", about a day) allows the organisms to anticipate periodical changes of geophysical time, and to adjust to these changes. Nearly all the cells in our body comprise molecular clocks that regulate and synchronize metabolic functions to a 24-hour cycle of day-night changes.
Two common operations for stress urinary incontinence help women achieve similar levels of dryness, according to a team of urologists and urogynecologists who compared the treatments in a large U.S. trial supported by the National Institutes of Health. The study is being released online May 17, 2010, by the New England Journal of Medicine to coincide with a presentation at the annual meeting of the American College of Obstetrics and Gynecology. Results will appear in the June 3 print edition.
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