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A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. If the regulation is lost, specialized cells cannot develop correctly during development. In adulthood, the specialized cells may forget their identity and develop into cancer cells.
When defending his 2007 attempt to make human papillomavirus (HPV) vaccinations mandatory for young girls in Texas, pointed out that both of his parents were cancer survivors and proclaimed, "I hate cancer." When asked to justify continued spending on abstinence-only education, despite the fact that it didn't seem to be budging Texas' high rates of teen pregnancy, he said, "I can tell you from my own life that abstinence works."
A landmark study to be published in the October 30, 2014 print edition of the journal Nature provides new insight into the function of an enzyme related to the BRCA1 breast-cancer protein. The study by a team at Penn State University is the first to produce a detailed working image of an enzyme in the Polycomb Repressive Complex 1 (PRC1) - a group that regulates cell development and is associated with many types of cancer.
International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.
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