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Pat Levitt, PhD, Chief Scientific Officer at Children's Hospital Los Angeles and Simms/Mann Chair in Developmental Neurogenetics, received a $3.7M grant from the National Institute of Mental Health to study development of neural circuits.
In a paper published January 31 in the journal Molecular Psychiatry, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) reveal how antipsychotic drugs interfere with normal metabolism by activating a protein called SMAD3, an important part of the transforming growth factor beta (TGFbeta) pathway.
Scientists have discovered a natural preservative capable of destroying a whole class of bacteria, including E.coli and listeria and now food can be made to remain fresh and last for years. There would also be no need to refrigerate produce treated with the preservative, called, bisin, which is produced by harmless bacteria.
Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step in understanding the molecular mechanisms of liver cancer progression and could lead to novel therapies for the disease.
High school football and wrestling athletes experienced the highest rate of severe injuries, according to the first study to examine severe injuries - injuries that caused high school athletes to miss more than 21 days of sport participation among a nationally representative sample of high school athletes. Severe injuries accounted for 15 percent of all high school sport-related injuries.
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