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Black skin cancer, also known as melanoma, is particularly aggressive and becoming increasingly common in Switzerland. Despite intensive research, however, there is still no treatment. Researchers from the University of Zurich have now discovered a gene that plays a central role in black skin cancer. Suppressing this gene in mice inhibits the development of melanoma and its proliferation - a discovery that could pave the way for new forms of therapy.
The word 'avalanche' is generally associated with violent and unexpected events - such as rockslides, or the sudden collapse of unstable drifts of snow. But in brain research, avalanches - intermittent cascades of electrical activity - are everyday occurrences that are not only peaceful, but actually reflect stability.
Cardiovascular disease, including heart disease and stroke, are among the top killers worldwide. Ischemic heart disease and stroke are the world's major killers, accounting for 15.2 million deaths in 2016. A high triglyceride level, combined with high low-density lipoprotein (LDL) cholesterol, is linked to atherosclerosis, which increases the risk for heart attack and stroke.
Scientists from the Gates Center for Regenerative Medicine at the University of Colorado School of Medicine are part of a consortium awarded $3.8 million from the U.S. Department of Defense to move discoveries in stem cell-created skin grafts into the manufacturing stage, bringing further hope to victims of debilitating inherited skin diseases.
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