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Researchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's disease (AD) that could lead to therapies focused on treating the neurodegenerative condition early in its progression.
Mortality rates are a poor measure of the quality of hospital care and should not be a trigger for public inquiries such as the investigation at the Mid Staffordshire hospital, argue experts in a paper published on bmj.com today.
Copper is an essential micronutrient that all organisms need to maintain healthy metabolism. But unless it is bound to proteins, copper is also toxic to cells. With a $1.3 million award from the National Institutes of Health, researchers at Worcester Polytechnic Institute will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa (P. aeruginosa), a leading cause of hospital-associated infections that is increasingly resistant to antibiotics, with the hope of discovering new drug targets that might allow cells in the body to use copper to fight back against this bacterial invader.
Armed with a new $1.8 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, dermatology researcher Nicole Ward, PhD, assistant professor of dermatology and neurosciences at Case Western Reserve School of Medicine, will lead a study examining the link between psoriasis and heart attack and stroke.
Peripheral artery disease develops silently, narrowing blood vessels for decades until the supply of nutrients and oxygen falls low enough to cause cramps and leg pain.
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