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During the process of SARS-CoV-2 infection, once the virus penetrates the host cell, two open reading frames, ORF1a and ORF1ab, are translated. ORF1ab is responsible for the production of 16 nonstructural proteins (nsp). Several viral proteases such as 3CLpro and PLpro (papain-like protease) produce 1-16 nsps. A new study has been published in bioRxiv* preprint server, which deals with identifying drugs that are effective as PLpro inhibitors.
Columbia University Medical Center has received a $5 million gift from Edward S. Reiner to establish the Reiner Center for Behavioral and Psychosomatic Medicine, the only center of its kind in New York City.
Airplanes are known to be medium for spreading airborne infections mainly because of the number of people including some with contagious infections such as flu, being clubbed together in a closed space.
Curcumin, the compound that gives curry powder its yellow/orange color, may inhibit the adverse effects of nicotine in patients with head and neck cancer who continue to smoke.
Parkinson's disease itself does not increase the risk of impulse control problems such as compulsive gambling and shopping that have been seen in people taking certain drugs for Parkinson's disease, according to new research published in the January 8, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.
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