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Researchers at Okayama University report in Scientific Reports how the overloading of protein transport mechanisms affects cell functioning. Over-expression of different types of target proteins leads to cellular growth defects, and the mechanism for transporting proteins out of a cell nucleus has the lowest over-expression tolerance.
It's the most common form of skin cancer, but in its advanced stages, basal cell carcinoma has the potential to become disfiguring and life threatening. An international phase 2 study headed by Mayo Clinic led to the recent Food and Drug Administration approval of the first drug of its kind to help advanced basal cell carcinoma patients who have few treatment options.
Gonadotropin-releasing hormone analogue given alongside growth hormone during puberty in order to increase adult height does not have long-term metabolic health consequences in children born small for gestational age, research shows.
As the world reaches a tipping point in the AIDS fight, (RED) and its iconic partners Apple, Bank of America, The Coca-Cola Company and Starbucks marked World AIDS Day 2014 by rallying millions of people around the AIDS fight, and raising money for the Global Fund to fight AIDS, TB and Malaria.
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