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In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell's membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production, Rockefeller University researchers and a colleague in Italy have gained new insight into this complex molecular process.
Fewer patients undergoing aortic valve replacement (AVR) are being re-hospitalized in the year following surgery, indicating the surgery is safer and the recovery has become easier, according to an article in the February 2015 issue of The Annals of Thoracic Surgery.
Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.
New research conducted in adolescent rodents provides insights on the mechanisms behind anorexia nervosa and points to a potential treatment strategy.
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