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Point-of-care testing is transforming healthcare: this type of testing helps patients get diagnosed and treated faster, and also makes it easier for patients in remote areas to have access to medical testing.
As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they need the proteasome for their uncontrolled growth. Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way. New medication could be developed on the basis of this previously unknown binding mechanism.
A new study published in the journal Radiology in February 2020 reports that performing a CT (computed tomography) scan of the chest increases the diagnostic rate and outperforms the reverse-transcription polymerase chain reaction (RT-PCR) tests currently utilized. The researchers recommend using chest CT to screen symptomatic patients for COVID-19 infections rather than the less sensitive RT-PCR.
In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. - who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country - outlines the molecular origins for differences in how well certain drugs work among distinct populations.
The National Institutes for Health has awarded Dr. Christian Grov and his colleagues $2.4 Million to launch a 2-year nationwide HIV prevention study of gay and bisexual men.
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