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In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy, which is also commonly observed in Alzheimer disease.
A Scientific American article examines recent efforts to tackle neglected tropical diseases (NTDs). The author writes "NTDs have plagued humankind for thousands of years. … What is new, however, is that donors, drugmakers, health ministries in low- and middle-income countries, the World Health Organization (WHO), and public-private partnerships are linking their efforts to combat the NTDs in a more coordinated and systematic way."
Leica Microsystems has launched two instruments of the laser microdissection microscope series, the Leica LMD6 and the LMD7, with LED illumination for transmitted light. Users can now choose between halogen and LED illumination. LEDs are an energy-efficient light source providing homogenous illumination and a constant color temperature.
The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause of breast cancer deaths. Surprisingly little is known about the control of this process and how it might be interrupted to prolong the lives of women with breast cancer.
Using morphine to fight the pain associated with abdominal surgery may paradoxically prolong a patient's suffering, doubling or even tripling the amount of time it takes to recover from the surgical pain, according to researchers at the University of Colorado Boulder.
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