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News Archive
Hyperion Therapeutics, Inc. announced today that its investigational compound glycerol phenylbutyrate (HPN-100) has been granted Fast Track Designation by the U.S. Food and Drug Administration (FDA) as adjunctive therapy for the chronic management of urea cycle disorders. Hyperion recently completed its phase III trial which was conducted under a Special Protocol Assessment (SPA) agreement with the FDA. The Company plans to announce results from that trial later this year.
Ardea Biosciences, Inc. announced positive, preliminary, top-line results from its Phase 2b monotherapy study of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout. In this 28-day, randomized, double-blind, placebo-controlled, dose-escalation study, 123 gout patients with hyperuricemia (serum urate levels greater than or equal to 8 mg/dL) received 200 mg once-daily (qd) RDEA594, 400 mg qd RDEA594, 600 mg qd RDEA594 or matching placebo.
The bipartisan spending deal announced Tuesday night by Senate Budget Chairman Patty Murray, D-Wash., and House Budget Chairman Paul Ryan, R-Wis., barely qualifies as a tweak. It would not make meaningful progress on reducing projected deficits, ... BY any measure it is a small-bore deal, but it as at least something -; a toehold that prevents a serious fall and might, optimistically, enable a climb to safety. ... It would also partially undo the inflexible across-the-board spending cuts known as sequestration. Longer term, the accord could signal the beginning of a more constructive relationship in Congress (12/10).
A study recently published in Nature Genetics provides new evidence that the genetic makeup of the embryo may cause the appearance of tumors in adult life. These results bear out the growing theory that some tumors may have an extremely early origin, tracing to the individual's embryonic development, while offering new clues to understand the genetic causes of certain kinds of cancer, and their prevention and treatment.
Social media influencers vaping glamorously into their social media feeds are often not doing so for free. And new research suggests that calling out their pay-to-play posts as advertisements in a plain, obvious way might have an impact on young people.
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