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Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) -; a rare and hard-to-treat cancer.
In a paper published January 31 in the journal Molecular Psychiatry, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) reveal how antipsychotic drugs interfere with normal metabolism by activating a protein called SMAD3, an important part of the transforming growth factor beta (TGFbeta) pathway.
Do infants only start to crawl once they are physically able to see danger coming? Or is it that because they are more mobile, they develop the ability to sense looming danger? According to Ruud van der Weel and Audrey van der Meer, from the Norwegian University of Science and Technology in Trondheim, infants' ability to see whether an object is approaching on a direct collision course, and when it is likely to collide, develops around the time they become more mobile. Their findings have just been published online in the Springer journal Naturwissenschaften.
Dr. E. Premkumar Reddy from Temple University School of Medicine and colleagues, in a study examining the effects of Plk1 inhibitor ON01910 on tumor growth in several animal models have found that a small molecule inhibitor of polo-like kinase1 (Plk1) could lead to a new avenue for targeted cancer therapy.
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