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Called BRIGHTs, the tiny probes described in the online issue of Advanced Materials on Nov. 15, bind to biomarkers of disease and, when swept by an infrared laser, light up to reveal their location.
Tracking blood flow in the laboratory is an important tool for studying ailments like migraines or strokes and designing new ways to address them. Blood flow is also routinely measured in the clinic, and laser speckle contrast imaging (LSCI) is one way of measuring these changes; however, this technique requires professional-grade imaging equipment, which limits its use.
New findings suggesting that bacteria in the mouth and/or intestine can affect the the outcome pathogenesis of atherosclerosis and lead to new treatment strategies, reveals research from the University of Gothenburg, Sweden.
Studying a cycle of protein interactions needed to make fat, Johns Hopkins researchers say they have discovered a biological switch that regulates a protein that causes fatty liver disease in mice.
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