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Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.
Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes-;tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.
A devastating vascular disorder of the brain called CADASIL, which strikes young adults and leads to early dementia, often is misdiagnosed as multiple sclerosis, Loyola University Health System researchers report.
At an event on Friday in Seattle, USAID Administrator Rajiv Shah discussed foreign aid efficacy and ways "to streamline the federal agency and to help make the whole U.S. aid budget easier to understand and track," the Associated Press/Seattle Times reports. Shah said that the Obama administration is concerned about foreign aid transparency and its effectiveness, adding: "The president continues to live up to the overall commitment to develop foreign assistance."
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