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YM BioSciences Inc., announced the conclusion of dose-escalation in the Phase I portion of its Phase I/II clinical trial of CYT387 at Mayo Clinic in patients with myelofibrosis. In total, 21 patients were treated in Phase I, with no voluntary withdrawals reported. CYT387 has shown significant activity in reducing spleen size and controlling constitutional symptoms in these patients.
One in five prescriptions in primary care for the elderly is inappropriate, say the authors of a systematic review.
Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Express this week.
Safe, in-person school during the COVID-19 pandemic requires research that involves community engagement in underserved or vulnerable areas of the United States, writes Alison Cernich, Ph.D., deputy director of NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and colleagues.
Reproductive medicine is one of today's most exciting scientific and clinical areas. Every month there are announcements of medical 'firsts', new rulings by regulatory bodies or ethical controversies. These often spark a heated debate among practitioners in the field, ethicists, legislators, the media and the public. ESHRE's Annual Meeting is the forum where more than 9,000 of the world's leading experts in reproductive medicine gather to give a public presentation of their latest research findings.
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