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Aeterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today reported final results on the clinical activity of perifosine (KRX-0401), the Company's novel, potentially first-in-class, oral anticancer agent that inhibits Akt activation in the phosphoinositide 3-kinase pathway, in combination with capecitabine (Xeloda) as a treatment for advanced, metastatic colorectal cancer.
Payment incentives implemented with a commercial accountable care organization (ACO) initiative in Massachusetts -Blue Cross Blue Shield's Alternative Quality Contract (AQC) - were associated with lower spending for Medicare enrollees served by the provider groups participating in the AQC, findings that suggest that evaluations of ACO programs may need to consider the implications for other patient populations to assess their full clinical and economic benefits, according to a study in the August 28 issue of JAMA.
A recent study evaluating the use of force by police against children found that Black and Hispanic adolescents are significantly more likely to die from shootings related to police intervention compared to non-Hispanic white adolescents.
Results of a European study in this week's issue of THE LANCET suggest that delaying delivery by a few days is as effective as immediate delivery for babies who have experienced fetal trauma. The study also showed that fetuses delivered without delay at 30 weeks or younger had an increased risk of infant disability compared with delayed delivery.
Politico reports that support among the public for the health overhaul dipped during the last month, even as the "percentage of Democrats who say they'll go to the polls to defend the law rose. … According to the Kaiser Family Foundation October Tracking Poll out Monday morning, overall support for the law has dropped to 42 percent — down seven points in a month (Kaiser Health News is a program of the Kaiser Family Foundation).
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