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Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert their therapeutic effects has not been clear. Now, a research team from the University of South Florida using animal models of stroke has found that the HUCBCs are most beneficial in preventing neuron loss when the Akt signaling pathway is activated by secretions from the HUCBCs and that Akt activation subsequently impacts a specific gene involved in reducing inflammation.
A review of previous studies indicates that use of a class of medications known as "incretin-based therapy", which act via certain pathways that affect glucose metabolism may provide modest effectiveness and favorable weight change outcomes for the treatment of type 2 diabetes and may represent an alternative to other hypoglycemic therapies.
Individuals who have persistent high blood pressure are at increased risks of a number of serious medical conditions, including heart failure.
University at Buffalo biophysicists have found a protein in tarantula venom that shows promise as a potential therapy for muscular dystrophy (MD). They have formed a start-up biotech company in Buffalo - Rose Pharmaceuticals - to advance the drug to clinical trials.
Canada's investments in drug information systems (DIS) will generate $436 million in cost savings and efficiencies in 2010, announced Richard Alvarez, President and CEO, Canada Health Infoway (Infoway). The findings are outlined in an independent study commissioned by Infoway, released today.
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