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Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.
One of the big questions for which there is still no clear answer in biology is how, based on the four universal letters that make up DNA, it is possible to generate such different organisms as a fly or a human, or the different organs and tissues they comprise. In recent years, researchers have discovered that the system is much more complicated than was originally thought.
Multi-resistant bacteria represent a major problem not only in hospitals but also in animal husbandry. A study of the University Bonn describes how a farmer successfully eliminated these pathogens entirely from his pig stable. However, the radical hygiene measures taken in this case can only be applied in individual cases. Nevertheless, the work has yielded a number of recommendations - not only for farms but also for hospitals. The study appeared in the Journal of Applied and Environmental Microbiology.
Research being conducted into stroke needs to slow down and take stock if a therapeutic breakthrough is ever likely to happen, says a leading stroke expert.
A research team at Nagoya University in Japan has revealed that narrow-range ultraviolet (UV) irradiation using light emitting diodes (LEDs) safely increases serum vitamin D levels in aging mice and thereby prevents the loss of their bone and muscle mass.
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