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A research team at the National Institute of Standards and Technology (NIST) studying sugar-coated nanoparticles for use as a possible cancer therapy has uncovered a delicate balancing act that makes the particles more effective than conventional thinking says they should be. Just like individuals in a crowd respecting other people's personal space, the particles work because they get close together, but not too close.
Frailty measurements have become increasingly important in assessing surgical risk in patients with mitral valve disease, and research published online today in The Annals of Thoracic Surgery shows that frailty plays a significant role in outcomes following mitral valve procedures.
Purisys LLC, a leading supplier of active pharmaceutical ingredients (APIs), contract development and manufacturing (CDMO) services, and pharmaceutical reference materials, today announced that it has obtained two additional global ISO certifications: ISO 17025 (Testing and Calibration Laboratories) and ISO 17034 (Reference Materials Producers).
UT Southwestern Medical Center researchers have determined the specific type of cell that gives rise to large, disfiguring tumors called plexiform neurofibromas, a finding that could lead to new therapies for preventing growth of these tumors.
When cells cannot carry out the tasks required of them by our bodies, the result is disease. Nanobiotechnology researchers are looking for ways to allow synthetic systems take over simple cellular activities when they are absent from the cell. This requires transport systems that can encapsulate medications and other substances and release them in a controlled fashion at the right moment. The transporter must be able to interact with the surroundings in order to receive the signal to unload its cargo.
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