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Idera Pharmaceuticals today announced that it had completed patient enrollment in its randomized, double-blind, placebo-controlled Phase 2 trial of IMO-3100 in patients with moderate-to-severe plaque psoriasis. IMO-3100 is an antagonist of specific Toll-like Receptors (TLRs) that the Company is developing for the treatment of psoriasis and other autoimmune diseases.
Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.
Retired NFL football players are at higher risk for mild cognitive impairment, which can be a precursor to Alzheimer's disease, a Loyola University Health System study has found.
Even though nurses routinely disclose nursing errors to their patients, a new study published in the January 2009 issue of The Joint Commission Journal on Quality and Patient Safety shows that nurses often are not included when physicians tell patients about more serious mistakes.
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