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Spinifex Pharmaceuticals, an Australian pain drug development company, today announced the first patients have been treated in its Phase 2 clinical trial of EMA401 in postherpetic neuralgia (PHN), a painful condition that develops in some patients following herpes zoster (shingles) and where existing therapy does not relieve pain in all individuals.
Since the 2006 launch of USAID's Neglected Tropical Disease (NTD) Control Program, which is managed by RTI, "more than 447 million NTD treatments have been provided to more than 82 million people," the Global Network for Neglected Tropical Diseases' "End the Neglect" blog reports.
New research raises the possibility that the critically short supply of livers for organ donation could be expanded by treating so-called "marginal" livers with a substance that protects them from damage after being connected to recipients' blood supplies.
A protein known for helping cells withstand stress may also act as a switch that triggers free-swimming Schistosoma larvae to begin penetrating the skin and transforming into the parasitic flatworms that burden more than 240 million people worldwide with schistosomiasis.
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