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Spleen to the left, appendix to the right: In order for the body to sort itself out properly, two substances have to trigger a complex chain reaction, according to the latest findings at the University of Hohenheim.
ARIAD Pharmaceuticals, Inc. today announced results of preclinical studies on ponatinib, its investigational pan-BCR-ABL inhibitor, showing potent inhibition of all four members of the fibroblast growth factor receptor (FGFR) family of tyrosine kinases that are abnormally expressed in multiple cancers. ARIAD scientists are presenting the data this morning at the American Association for Cancer Research (AACR) Annual Meeting in Orlando, Florida.
A new epilepsy gene, LGI2, has been found in the Lagotto Romagnolo dogs, known from their gift for truffle hunting. The gene discovery made by Professor Hannes Lohi and his research group at the University of Helsinki and the Folkhälsan Rsearch Center offers a new candidate gene for human benign childhood epilepsies characterized by seizure remission.
A recent study published in the preprint server medRxiv in September 2020 shows that the effect of climatic factors such as temperature and humidity is mediated mostly through human mobility. Thus, human behavioral changes are still the mainstay of containment rather than hoping for weather conditions to keep the virus at bay.
Over recent years, Zika virus has spread eastward from Africa and Asia, leading to an epidemic in the Americas. Now, researchers comparing American, Pacific and Southeast Asian subtypes of the virus in PLOS Neglected Tropical Diseases have concluded that the American-subtype strain has the highest ability to grow both in vitro and in vivo.
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