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The heart maintains a careful balancing act; too soft and it won't pump blood, but too hard and it will overtax itself and stop entirely. There is an optimal amount of strain that a beating heart can generate and still beat at its usual rate, once per second.
Researchers at the RIKEN Quantitative Biology Center and the University of Tokyo have developed a method to visualize cancer metastasis in whole organs at the single-cell level.
In neurodegenerative diseases, clumps of insoluble proteins appear in patients' brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer's disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals. For years, these other proteins were thought to be accidental inclusions in the aggregates, much as a sea turtle might be caught in a net of fish.Now, in a surprising new finding, researchers at the University of California, San Francisco, report that many of the proteins present as minor components of disease aggregates actually clump together as a normal part of aging in healthy individuals.
The U.N. Development Programme on Thursday in Mexico City launched the Human Development Index 2013, which "combines measures of life expectancy, literacy, school enrollment and gross domestic product per capita," the U.N. News Centre reports.
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