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Cholesterol influences the health of our hearts and blood vessels. Conventional treatment attempts to reduce the level of "bad" cholesterol, LDL cholesterol, in the blood plasma. The opposite approach, which involves increasing the concentration of "good" HDL cholesterol using nicotinic acid, has proven unpopular among patients up to now. The reason for this is that treatment with nicotinic acid has an unpleasant but harmless side-effect: the drug makes patients turn quite red in the face. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now discovered the mechanism behind this effect, which is known as flushing. This will enable the development of flush inhibitors and thereby the more effective prevention of cardiovascular diseases.
Children from urban areas of New York City who engaged in vigorous daily exercise had greater exposure to black carbon, a traffic-related pollutant, than children who were less active, according to a study by a multidisciplinary team of researchers from Columbia University's College of Physicians & Surgeons and Columbia's Mailman School of Public Health.
An analysis of North Carolina birth and educational records suggests that induction (stimulating uterine contractions prior to the onset of spontaneous labor) and augmentation (increasing the strength, duration, or frequency of uterine contractions with spontaneous onset of labor) during childbirth appears to be associated with increased odds of autism diagnosis in childhood, according to a study by Simon G. Gregory, Ph.D., of Duke University Medical Center, Durham, N.C., and colleagues.
People with a high level of mercury exposure in young adulthood are at an increased risk for developing diabetes later in life, report researchers.
Researchers at the University of Pennsylvania School of Medicine, in collaboration with scientists at the City University of New York, have identified a striking dysregulation in neuronal receptor activity in the postmortem brain tissue from patients with schizophrenia.
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