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CureVac AG, a fully-integrated biotechnology company pioneering mRNA-based drugs, today announced it has initiated a Phase I study assessing the intratumoral application of its novel RNAdjuvant technology in patients with superficial solid tumors that are easily accessible for repeated intratumoral injections. RNAdjuvant is designed to amplify the scope and quality of an immune response when used alone or in combination with other immune therapies.
UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related strains of mice often used to study addiction and behavior patterns.
Many people survive their cancers, but end up dying of cardiovascular disease. New research from Wake Forest Baptist Medical Center finds that CVD risk factors may be overlooked during survivorship care.
Five genetic regions have been identified that are unique to the most virulent strain of Clostridium difficile (C. difficile), the hospital superbug. Researchers writing in BioMed Central's open access journal Genome Biology studied the genome of the bacterium, looking for genes relating to motility, antibiotic resistance and toxicity.
Extremely premature infants born at 22 to 25 weeks of gestation have low rates of survival, and many of those infants who live have severe or moderate neurodevelopmental impairments. Thus, clinicians and families face the extremely difficult decision to either provide active, potentially lifesaving treatment at birth, or just provide comfort care.
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